BURKITT'S LYMPHOMA: CASE REPORT WITH 3-YEAR FOLLOW-UP

Resumo

Introduction: Burkitt's lymphoma is a neoplasm that originates from mature B lymphocytes. It predominantly affects jaw bones, mostly in males and children. Methods: This work aims to report a case of a 12-year-old male patient who presented at FACSETE’s dental clinic with complaints of diffuse pain in several regions of the dental arches and swelling in the left mandibular vestibular fold. The teeth in the affected region showed slight mobility. Imaging exams revealed changes in the bone trabeculae, loss of the lamina dura in some teeth, and thinning and perforation of the cortical bone in the left mandible. An incisional biopsy was performed, and histological findings suggested a lymphoproliferative lesion. Results: Immunohistochemistry confirmed diffuse lymphoid proliferation of medium-sized cells with a "starry sky" appearance, and Ki-67 labeling index estimated at 100%, consistent with Burkitt's lymphoma. The patient was referred to São Lucas Hospital for further diagnostic evaluation and chemotherapy. Approximately 60 days later, the lesion regressed, with bone neoformation in the area, and orthodontic treatment was initiated. Conclusion: The patient is currently stable without any alterations in bone or soft tissues.